The development of novel therapies such as abiraterone acetate and sipuleucel-T has improved the outlook for patients with advanced-stage and castration-resistant prostate cancer. However, the ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Researchers studying mesenchymal stem cells (MSCs) face significant challenges with traditional endpoint assays that provide only limited snapshots of the differentiation process. The inability to ...

Embryonic stem (ES) cells derived from pluripotent cells of early embryos possess an almost unlimited self-renewal capacity and the potential to differentiate into the many cell types of mammalian ...