From birth-month signatures to global climate gradients, emerging evidence indicates that seasonal light, temperature, and ...

Discover how Treg cell therapies rethink precision medicine for autoimmune diseases like type 1 diabetes, MS, and transplant rejection.

Fc receptors for immunoglobulin G (FcγRs) link humoral and cellular immunity by binding antigen–IgG immune complexes and internalizing the complexes for efficient antigen presentation. FcγRs comprise ...

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

In 1798, Edwards Jenner inoculated individuals with 'fluid from cowpox blisters', which prevented smallpox disease, thus creating the first vaccine. Thereafter, the concept and use of vaccination ...

Chimeric antigen receptor (CAR) T-cell therapy for blood cancers appeared less toxic, and patients' hospital stays were days shorter, when they also had autoimmune disease before starting the ...

Immunotherapy for advanced melanoma induces serologic and clinical manifestations of autoimmunity. We assessed the prognostic significance of autoimmunity in patients with stage IIB, IIC, or III ...

As shown in Figure 1, by 60 years of age, the cumulative incidence of diabetes among monozygotic twins who were initially discordant for diabetes was 65% (95% confidence interval [CI], 39 to 91), and ...

The term autoimmunity refers to the failure of the human body's immune system to recognize its cells and tissues as "self." In contrast, humoral and cell-mediated immune responses by B lymphocytes and ...

Scientists have revealed a novel mechanism through which the immune system controls autoimmunity and cancer. In the special focus of the researchers were regulatory T cells -- a type of white blood ...