Bile acids are essential molecules the liver produces that play a critical role in digestion. They help us absorb fat-soluble vitamins and cholesterol from our food. However, bile acids can become a ...
Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors. It has made an incredible impact on treating cancers in many different organ ...
Hosted on MSN
Bile imbalance linked to liver cancer: Key molecular switch sheds new light on treatment interventions
A new study reveals how a critical imbalance in bile acids—the substances made by the liver that help digest fats—can trigger liver diseases, including hepatocellular carcinoma (HCC), the most common ...
Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors. It has made an incredible impact on treating cancers in many different organ ...
With smart DMPK strategies, cross-domain collaboration, and strong CDMO support, companies are pushing past the challenges of ...
(A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts the intermediate ...
The image depicts gut microbes producing secondary bile acids to support the host’s immune defense against cancer. Microbiota-derived bile acids (shown in light green) blocked the androgen receptor ...
The gut microbiota have a known role in modulating gut immune homeostasis. Largely, through the development and function of host immune cells, including T helper cells expressing interleukin-17A. It ...
6don MSN
Microbially produced secondary bile acids accelerate colorectal cancer development, study shows
For the first time, a team of experts from the Technical University of Munich (TUM), RWTH Aachen University, and the German ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback