The authors compared the CD4+ T-cell counts and HIV-1 RNA viral loads of 383 patients who were either mono-infected with HIV or co-infected with HTLV-1/HIV. They confirmed that co-infected patients ...

Idiopathic CD4 T Lymphocytopenia (ICL) is a rare immunological syndrome defined by persistently low CD4+ T-cell counts, typically below 300 cells/µL, in the absence of human immunodeficiency virus ...

In this study, we revealed the pulmonary pathogen profiles of immunosuppressed ICU patients based on CD4+T-cell counts: the ...

July 30, 2010 (Vienna, Austria) — Although initiation of highly active antiretroviral therapy (HAART) against HIV is associated with a lower risk for progression to AIDS, and a lower risk for ...

Importantly, immune checkpoint blockade can partially reverse CD4+ T cell exhaustion, restore effector function, and enhance therapeutic outcomes, highlighting their pivotal role in determining ...

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with longer PFS, suggesting T-cell composition may serve as a biomarker to ...