A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...
A new cross-coupling reaction weds chiral carboxylic acids, such as proline derivatives, to alkyl iodides while preserving ...
The catalytic hydrogenation of carboxylic acids—the reduction of R–COOH functionalities to alcohols or hydrocarbons under a hydrogen atmosphere—stands at the interface of sustainable chemistry and ...
Amines and carboxylic acids are abundant chemical feedstocks that are nearly exclusively united via the amide coupling reaction. The disproportionate use of the amide coupling leaves a large section ...