Unraveling the mysteries of how biological organisms function begins with understanding the molecular interactions within and ...

Cancer cells expand through mutations – but not just through mutations. They also change their behavior in the absence of underlying genetic alterations. Such plasticity helps the cells both adapt to ...

A small subpopulation of highly plastic cancer cells has been found to be for cancer progression and treatment resistance.

T cells are central mediators of autoimmune disease pathogenesis, yet their functional states are not defined solely by antigen recognition or canonical ...

A small number of cancer cells with the ability to change their identities and behaviors appear to be a key driver of cancer progression and its ability to evolve resistance to treatment, Memorial ...

“There has never really been an integrated explanation as to why cancer cells develop plasticity,” said Antonio Iavarone, M.D. “That’s what our study does. We’ve now revealed how the plasticity of ...

Unraveling the mysteries of how biological organisms function begins with understanding the molecular interactions within and across large cell ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more ...

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers headed by a team at The Ohio State University College of Medicine have shown how ...

Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...