This Collection supports and amplifies research related to SDG 3. This is a joint Collection across npj Aging, Nature Aging, Nature Metabolism, Nature Cell Biology and Scientific Reports. Please see ...

New research suggests a high-salt diet may trick the immune system into prematurely aging the blood vessels, leading to ...

Cellular senescence is a state characterized by permanent cell-cycle arrest, increased expression of markers such as p16^INK4a and p21^CIP1/WAF1, elevated DNA damage signals (e.g., γ-H2AX) and a ...

Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, ...

Senescence, aging, and age-related diseases represent complex biological phenomena with significant impacts on human health, and metabolism and metabolomics play pivotal roles in understanding their ...

A new set of drugs exploit a recently revealed weakness in "zombie-like"—or senescent—cells that could lead to new treatments ...

Triple-negative breast cancer (TNBC), particularly the luminal androgen receptor (LAR) subtype, presents significant ...

Cellular senescence is a state where cells permanently stop dividing but remain metabolically active, often in response to stress or damage. Senescent cells are known to play a key role in wound ...

Chemotherapy kills cancer cells, but it also leaves behind something troubling: damaged cells that stop dividing yet refuse ...

Researchers built an immune-aging clock from 1.2 million cells, revealing T cells as key indicators of immune aging. They ...