In many areas of chemistry the synthesis of chiral compounds is a target of increasing importance. They play a vital role in biological function and in many areas of society and science, including ...

The recognition of chirality in bioactive molecules is as old as modern organic chemistry itself. Pioneering work by Jean-Baptiste Biot, Louis Pasteur, Emil Fischer, and J. vant Hoff established ...

New research shows how metal surfaces that lack mirror symmetry could provide a novel approach towards manufacturing pharmaceuticals. New research shows how metal surfaces that lack mirror symmetry ...

Researchers have designed and built a new chemical tool inspired by natural metal-containing enzymes in living organisms. The product, a tetrahedral "chiral zinc", maintains its shape for years, ...

An experiment designed to untangle spectroscopy signals coming from a complex mix of molecules and nanoparticles has revealed a surprising detail about the handedness of the self-assembled ...

The commercial availability of an increasing diversity of enzymes has led to the growing use of biocatalysts for API synthesis. The complexity of both small-molecule and large-molecule drugs is ...

The synthesized double-helical monometallofoldamers exhibiting controllable chirality switching can lead to the development of novel artificial supramolecular systems for molecular information ...

Catalysis for asymmetric reactions is generating tremendous academic and industrial interest, even if it is not yet widely used in pharmaceutical production. Several critical considerations surface ...