In patients receiving percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI), post-conditioning therapy reduces infarct size and edema by one-third compared ...
Children eligible for stem cell transplantation will have several preliminary appointments for tests and blood work scheduled before being admitted for transplant. These pre-transplant evaluations and ...
Avrobio is working to make conditioning, a necessary step for some gene therapies, safer. But it’s not stopping at improving current approaches—the company is teaming up with Magenta Therapeutics to ...
ORLANDO -- Myeloablative conditioning (MAC) led to a long-term survival benefit versus reduced-intensity conditioning (RIC) for patients with acute myeloid leukemia (AML) treated with hematopoietic ...
A company developing a drug to address the growing need for safe ways to condition patients receiving cell and gene therapies is partnering with a firm developing single letter-level gene editing to ...
TBI has traditionally been an integral part of pre-transplantation conditioning. However, it is associated with substantial toxicity and undesirable long-term side effects. 2 On the basis of these ...
Quantitative analysis of leucocyte subsets by multiplex PCR using short tandem repeat (STR) markers and fluorescence detection system has been a useful tool for the assessment of chimeric states even ...
As a young pediatric oncologist, Kevin Heller was struck by the power of bone marrow transplants. While working at Memorial Sloan Kettering Cancer Center in the early 2000s, he saw how hematopoietic ...
Please provide your email address to receive an email when new articles are posted on . A base-edited cell therapy increased fetal hemoglobin and reduced sickle hemoglobin. No patients who received ...
Please provide your email address to receive an email when new articles are posted on . Three patients with sickle cell disease who received the investigational gene therapy ARU-1801 achieved and ...
Nkarta Therapeutics’ off-the-shelf natural killer cell therapy appears to be most effective against blood cancer when used with a specific lymphodepletion regimen. But that’s not what most patients ...