A “digital bioprocess replica” is, as the name suggests, a computer model of a bioprocess. The aim is to simulate the entire process, including all critical parameters and quality attributes, to ...

Process analytical technology (PAT), a quality assurance program for the pharmaceutical industry developed by the US Food and Drug Administration, enables pharmaceutical manufacturers to control ...

Aim: To demonstrate the potential of in-line nanoparticle size measurements using the NanoFlowSizer (NFS) as a PAT method. To achieve real-time process control by establishing automated regulation of ...

GEN: Can you speak to your experiences with scale-down screening model systems? Do you have a preference? Sieck: The best screening model depends on specific needs. An ideal small-scale model should ...

Increasingly tight tolerances and rigorous demands for quality are forcing chipmakers and equipment manufacturers to ferret out minor process variances, which can create significant anomalies in ...