Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...

On the left side, in vitro preassembled DNA circuits are delivered into living cells. Alternatively, on the right side, RNA pregates are autonomously transcribed from the chromosome or plasmids to be ...

Once disregarded as “junk DNA,” scientists now know that this molecular dark matter is crucial for determining gene activity in ways that keep us healthy—or cause disease. Exactly how this DNA shapes ...

Since the dawn of the computer age, researchers have wrestled with two persistent challenges: how to store ever-increasing ...

Scientists found that DNA’s phosphate groups can direct chemical reactions to make the correct mirror-image form of drug molecules. This breakthrough simplifies chiral drug production, reducing waste ...

For James Watson, DNA was everything — not just his life's work, but the secret of life itself. Over his long and storied career, Watson arguably did more than any other scientist to transform a ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing the entire repair sequence as it unfolds. Instead of freezing cells at ...