Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the brain is not static; neurons continually adjust the strength of their ...

Scientists have found that blocking microglia (specialist immune cells in the brain) prevents infant forgetting ("infantile amnesia") and improves memory in mice, suggesting that microglia may ...

Active dentate gyrus cells—those participating in memory formation—would produce the protein, thus becoming light-sensitive themselves. The idea was that after the memory had been encoded, it could be ...

Babies of every species from mouse to human rapidly forget things that happen to them-an effect called infantile amnesia. A type of brain immune cell called microglia might control this type of ...

Infantile amnesia is the global loss of episodic and contextual memories formed in early life. Our research shows that the engrams storing these memories endure in the brain into adulthood (in mice) ...

BUFFALO, N.Y. – Think of a time when you had two different but similar experiences in a short period. Maybe you attended two holiday parties in the same week or gave two presentations at work. Shortly ...

Schematic model showing how memory is consolidated in the prefrontal cortex and how circuitry through the amygdala shifts as hippocampal engram cells become silent and cortical engrams become active.

As far back as Plato and Aristotle, people believed that our memories had to be physical somethings that were stored somewhere in the brain. But only in modern times have we learned much about what ...