Though we all share common ancestors ranging from a few generations to hundreds of thousands of years, genealogies that relate all of us are often forgotten over time. A new McGill University-led ...

Sometimes, a small error in the sequence of DNA can lead to a very serious disease. Scientists have identified many mutations that arise in a single gene to cause an ...

A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...

The period between the 1920s and 1950s was a time of significant progress and exciting discoveries in gene therapy history and biomedicine. Groundbreaking advances in understanding inherited DNA and ...

A new genetic mapping strategy reveals how entire networks of genes work together to cause disease, filling in the missing links left by traditional genetic studies. The technique could transform how ...

In 1980, a landmark paper described restriction fragment length polymorphism (RFLP), a method predateding high volume DNA sequencing, that could be used to identify disease-causing genes. Ray ...

Melon (Cucumis melo) represents a model crop for exploring genetic diversity and trait mapping owing to its long history of domestication and worldwide cultivation. Recent advances have elucidated its ...

A research centre had mapped out Britain's genetic make-up and, in the process, revealed some interesting facts about the historical origins of its citizens. In particular, the map created by the ...

The ability of different genetic variants—changes to one or more building blocks of DNA—to cause disease, and to what extent, has historically been opaque. Geneticist and Crick group leader Greg ...