Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

A human female is born with all the egg cells she will ever have. The possibility for the development of new oocytes is zero. Given this constraint, it is crucial that these gametes remain healthy and ...

Human oocytes can last for up to 50 years—and a newly discovered metabolic pathway is key to this longevity. By Lauren J. Young Published Jul 22, 2022 2:45 PM EDT Get the Popular Science daily ...

One of the immutable truths about being alive is that we age. This happens at every level, down to our cells. When they divide, our cells copy our DNA into each new cell. But as the weeks, months, and ...

Examples of the human oocyte stages used in this study. On the left is an immature GV-stage oocyte recognizable by a visible cell nucleus (white arrow) called germinal vesicle (GV). On the right is an ...