In a recent study published in Nature Communications, researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP). Study: ...

A 41-year-old gravida 5 para 2113 at 32 and 4/7 weeks' gestation presented to labor and delivery with generalized pruritus of 3-days' duration. She had no outward signs of rash or pustules. She also ...

Intrahepatic cholestasis of pregnancy is a reversible form of cholestasis, in genetically predisposed individuals. Onset is late in pregnancy and clinically it is characterized by the presence of ...

Intrahepatic cholestasis of pregnancy is a gestation-specific liver disorder characterised primarily by pruritus and elevated serum bile acid levels, typically manifesting in the second or third ...

A recent study published in Frontiers in Medicine evaluated the effects of coronavirus disease 2019 (COVID-19) quarantine on outcomes in individuals with intrahepatic cholestasis of pregnancy (ICP).

Please provide your email address to receive an email when new articles are posted on . The FDA has issued a safety alert warning patients and health care providers of a “rare risk of intrahepatic ...

Pregnant patients should discontinue use of thiopurines if they develop intrahepatic cholestasis of pregnancy. The use of thiopurines (eg, azathioprine, 6-mercaptopurine, and 6-thioguanine) by ...

A pregnant person with a history of cytomegalovirus and elevated liver function tests presents with relentless, worsening pruritus. A 34-year-old woman presents to her obstetrician at 15 weeks’ ...

A new study found a strong connection between azathioprine exposure and development of ICP in women with systemic lupus erythematosus (SLE).

Progressive familial intrahepatic cholestasis (PFIC) is a rare genetic condition that prevents bile from properly draining from the liver. It often begins in infancy. PFIC can cause a range of ...