In a groundbreaking study, Stevens researchers show how colorectal cancers can evolve from mature intestinal cells that ...

In a recent study, Stevens researchers have shown how colorectal cancers can evolve from mature intestinal cells that revert ...

Patients receiving intensive cancer treatments—such as radiation or stem cell transplantation—often suffer from severe damage to the intestinal lining. This not only causes pain and complications but ...

Gut stem cells can detect invading bacteria and transform into bacteria-killing cells, revealing an unexpected immune defense ...

The intestinal epithelium undergoes one of the most rapid and continuous self‐renewal processes in the human body, driven by a pool of actively cycling Lgr5+ stem cells situated at the base of crypts.

MIT scientists have identified cysteine — an amino acid found in foods like meat, dairy, beans, and nuts — as a potent ...

A recent study comparing young and aged mouse intestinal tissues revealed a delicate balance between IFN-γ signaling and ERK/MAPK signaling as crucial for maintaining the intestinal stem cell ...

Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...

Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka, MD, PhD, was a postdoctoral scientist at Gladstone Institutes, studying genes.

When inflammation damages the intestinal lining, differentiated enterocytes and crypt base columnar stem cells (CBCs) revert to a regenerative, fetal-like state and form revival stem cells (revSCs).