Study met primary endpoint demonstrating barzolvolimab’s ability to potently deplete mast cells in the gastrointestinal tract Profound mast cell depletion did not result in improved clinical outcomes ...

HAMPTON, N.J., May 05, 2025 (GLOBE NEWSWIRE) -- Celldex announced today the presentation of histology data from the Company’s ongoing Phase 2 study of barzolvolimab in eosinophilic esophagitis (EoE).

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Sugimoto K; Kudo M; Sundaram A; Ren X; Huang K; Bernstein X; Wang Y; Raymond WW; Erle DJ; Abrink M; Caughey GH; Huang X; Sheppard D Allergic asthma is the most common form of asthma, affecting more ...

Chinese scientists have discovered a common mechanism by which structurally distinct proteins elicit an allergic reaction, showing they cause the formation of pores in epithelial airway cells. That ...

Researchers have created a nanotherapy that selectively targets and shuts down the immune cells responsible for causing an allergic response in mice, preventing anaphylaxis. Able to be tailored to ...

It has long been thought that only nerve and heart cells use electric impulses to communicate, while epithelial cells -- which compose the linings of our skin, organs and body cavities -- are mute, ...