Sometimes cancer cells are able to cross into the fluid that surrounds and protects your brain and spinal cord. Cancer drugs you take by mouth or through a vein can’t get through as easily.

Please provide your email address to receive an email when new articles are posted on . Early intrathecal therapy effectively resolved symptoms related to high-grade neurotoxicity among patients who ...

Baclofen (Gablofen, Lioresal, Ozobax) is a medication that treats stiff muscles and spasms, a condition called spasticity, that can happen to people with multiple sclerosis (MS) and other nerve ...

Intrathecal baclofen (ITB) therapy has evolved into a standard treatment for severe spasticity. After this therapy had been provided for 10 years, a retrospective chart review on 50 patients, ...

A novel indwelling subcutaneous intrathecal catheter circumvented the complex spine anatomy of patients with spinal muscular atrophy (SMA), a challenge when giving nusinersen via intrathecal injection ...

PHILADELPHIA (WPVI) -- Pain is one of the most common problems for cancer patients. They often struggle to find relief or with side effects from the powerful narcotics often used for pain. There's an ...

Practitioners from around the country who have extensive experience in intrathecal baclofen (ITB) therapy gathered in early 2004 to develop best-practice guidelines for ITB therapy. Discussion focused ...

Panelists discuss how emerging intrathecal gene therapy for older patients with spinal muscular atrophy (SMA) shows modest efficacy with fewer systemic adverse effects than intravenous administration, ...

Phase I study of vorinostat (suberoylanilide hydroxamic acid) in combination with temozolomide (TMZ) in patients with malignant gliomas (NABTC 04–03) No significant financial relationships to disclose ...

Reports of pump failure, dosing errors, as well as other possible safety issues have prompted the Agency to issue the alert to make prescribers aware of the dangers associated with using medications ...