PD-1 blocking treatment may convert TAMs from tumor-promoting to tumor-fighting, improving outcomes in metastatic clear cell kidney cancer. Higher levels of CD163-positive TAMs are linked to better ...

Our results provide mechanistic evidence that immune responses to EBV can directly damage the brain in MS,” said Olivia Thomas, PhD, assistant professor at the Department of Clinical Neuroscience at ...

At times, aging doesn’t become evident in wrinkles or in gray hair, it occurs deep inside your body, in cells that have ceased to divide but are still alive. These “zombie cells,” or senescent cells ...

Hypothyroidism is a significant risk factor for IPF, with a higher prevalence in IPF patients compared to the general population. Mendelian randomization confirmed the association between ...

Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...

The gastrointestinal tract is the biggest immune organ in mammals. The gut extends its influence all over the body through various links like the gut-liver axis, the gut-lung axis, and the gut-brain ...

People with severe chronic pain were far more likely to have elevated levels of eosinophils, a type of white blood cell, a new study found, hinting at an immune link to pain – but the rise in these ...

Scientists at Wake Forest University School of Medicine, in collaboration with researchers at Weill Cornell Medicine, have made a breakthrough in understanding why many cancer patients develop nerve ...

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this ...

For years Yale researchers David Breslow and Mustafa Khokha have worked together with a similar challenge in their sights – trying to capture the interplay between certain genes and the pediatric ...