Membrane proteins present significant technical challenges in drug discovery, yet their role in biology make them highly ...

Proteins designed by artificial intelligence (AI) are being considered for use in treating everything from snakebites to cancer. A Nature Communications paper, out this week, describes how Australian ...

Innovative approach expands drug discovery possibilities for targets beyond the reach of conventional methodTo be presented ...

Citrate is essential for the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a central role in this process and has previously been linked to a particularly ...

A research team has revealed the molecular steps that led to the emergence of this plant-specific vacuolar transport system. Their work shows that the acquisition of this pathway was driven by the ...

A team has clarified how in plants the boric acid channels, the conduits for the necessary element boron, are transported to the plasma membrane. Botanists have come to understand the channels and ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

Scientists at the VIB–VUB Center for Structural Biology have uncovered a counterintuitive principle that could reshape how membrane proteins are designed from scratch: Sometimes, making a protein less ...

A protein found only in microscopic tardigrades, one that allows them to survive extreme conditions like dehydration, can ...

This illustration shows how the membrane trafficking protein VAMP72 gradually changed during plant evolution to give rise to VAMP727, which functions in transporting storage proteins to vacuoles. The ...