Pirt is a membrane protein that is specifically expressed in the peripheral nervous system, where it has been shown to increase the sensitivity of the transient receptor potential vanilloid 1 channel ...
Figure 2: Pirt and P2X3 are co-expressed in bladder nerve fibres. We also examined the expression of Pirt in DRG tissues. Immunohistochemistry results showed that the fluorescence signals of Pirt were ...
Neuroscientists are a step closer to understanding pain sensitivity -- specifically why it's variable instead of constant -- having identified a gene that regulates a heat-activated molecular sensor.
Neuroscientists at Johns Hopkins are a step closer to understanding pain sensitivity - specifically why it’s variable instead of constant - having identified a gene that regulates a heat-activated ...
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