Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

By extending a naturally rigid bacterial protein by 50% while preserving geometry and stability, the study introduces protein ...

The way proteins move is often what gives them biological activity: they can open, close, twist, and rearrange themselves in ways that allow them to bind to other molecules or perform complex ...

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...

Illustration showing how integrating protein three-dimensional structures with artificial intelligence algorithms can predict synergistic or antagonistic effects of drug combinations, guiding safer ...

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert ...

While protein design is experiencing a period of rapid development and advancement, there’s one particularly challenging class of proteins that’s giving researchers a hard time: enzymes. Now ...