Ribosomal proteins, classically thought to function only as translational machinery, now appear to play a role in the HDM2-p53 pathway. Recent work by scientists at the University of Texas MD Anderson ...
Ribosomal subunit assembly and biogenesis constitute a fundamental process vital for cellular protein synthesis across all domains of life. This complex, multi-step pathway involves the transcription ...
A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice. The mutation was found to ...
Mitochondrial ribosomal protein family in cancers: Mechanistic insights and therapeutic implications
(A) MRPS29 interacts with ADAR2 and represses A-to-I RNA editing by disrupting the association of ADAR2 with dsRNA, which induces the accumulation of PDZD7WT in cells to promote cancer. (B) MRPL9 ...
Researchers recently discovered that a virus, FloV-SA2, encodes one of the proteins needed to make ribosomes, the central engines in all cells that translate genetic information into proteins, the ...
Lung adenocarcinoma may be cornered by a recent finding coming from a study published on Nov. 30, 2023, in the Proceedings of the National Academy of Sciences. This investigation has unveiled that a ...
This new review article highlights the critical role of ribosome biogenesis in liver health and disease progression. As the center of protein synthesis, ribosomes influence liver regeneration, ...
Researchers at Nankai University in Tianjin have identified a breakthrough biological target for treating age-related ...
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