New research has shown how brain cells acquire a cancerous mutation and spread across the cortex, opening a new path for ...
New research reveals that certain brain tumors may originate silently within normal brain cells long before a tumor forms.
This Collection supports and amplifies research related to SDG 3 - Ensure healthy lives and promote well-being for all at all ages. Cancer research has hugely benefitted from the growth in single-cell ...
IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young ...
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3D spatial mapping of tumor cell 'neighborhoods' reveals potential targets for personalized cancer therapy
Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...
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Unveiling IDH-mutant glioma's roots: A new path for early diagnosis
IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young adults under the age of 50.
Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...
Scientists have identified a new CAF subset in HNSCC using tissue cytometry and spatial transcriptomics. In two-thirds of cases, head and neck squamous cell carcinomas (HNSCC) require treatment with ...
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