Bacterial pathogens produce complex carbohydrate capsules that dominate surface chemistry, inhibit phagocytosis and induce immunological responses by the host. The pneumococcus, or Streptococcus ...
Streptococcus pneumoniae remains an important pathogen despite licensure of a seven-valent pneumococcal protein conjugate vaccine. As a result, serotyping strains remains of paramount importance to ...
Antibiotic-resistant bacteria is a serious public health threat. Understanding the biology of these bacteria—such as how they synthesise their protective capsules—is essential for developing new ...
Researchers uncover new differences in bacteria's sugar coat to aid pneumococcal vaccine development
Many disease-causing bacteria like Streptococcus pneumoniae (S. pneumoniae) are encased in a sugar layer called the capsular polysaccharide (CPS). This layer is often essential for infections. In a ...
To understand how this pathogen adapts to different locations in the body, and also how the host responds to the invading microbe, researchers at the University of Alabama at Birmingham, the ...
Vaccines that protect people from infection by Streptococcus pneumoniae, which kills up to one million children ever year worldwide, train the immune system to recognize the pathogen’s thick sugar ...
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