Our bodies’ nerve cells are important for transmitting electrical and chemical information between different parts of the brain and between the brain and other parts of the nervous system. One of the ...

Spinal motor neurons (blue) affected by SMA (right image) have significantly less expression of Kv2.1 potassium channel (yellow), decreasing their ability to fire (recordings on the top right of each ...

This high-throughput screening system is designed to identify compounds that decrease motor neuron hyperexcitability, a cardinal feature of ALS. Motor neurons derived from patients with ALS are ...