As we age, we don’t recover from injury or illness like we did when we were young. But new research from UC San Francisco has found gene regulators that turn genes on and off that could restore the ...
Background Intestinal fibrosis, a hallmark complication of Crohn’s disease (CD), frequently progresses to stricture formation and surgical intervention. Fibroblast metabolic reprogramming is important ...
On Wednesday, FibroBiologics, Inc. (NASDAQ: FBLG) submitted a new patent application with the U.S. Patent and Trademark Office (USPTO). The patent application covers a proprietary fibroblast-derived ...
Heart failure occurs when the heart can no longer pump blood efficiently to meet the body’s needs. Beyond weakened muscle cells, new research highlights the hidden role of fibroblasts—supporting cells ...
Scientists have mapped underappreciated scaffolding cells in skin, known as fibroblasts. They show for the first time how fibroblasts go 'rogue' in many different diseases affecting multiple organs – ...
Healing from any injury involves a delicate balance between scarring and inflammation — two processes that can wreak havoc as well as make repairs. When the injury is to the brain, the balance is that ...
A working model showing that CAFs exhibit profound amino acid reprogramming, especially the production of glycine, in CRC. CRC cell‐derived TGF‐β1 activates de novo glycine synthesis in CAFs, ...
18 F-labeled fibroblast activation protein inhibitor tracer (18 F-FAPI-42) PET imaging can detect fibroblast activation in the myocardium among patients with dilated cardiomyopathy (DCM), according to ...
Imagine this: you’re in the middle of an important project, juggling deadlines, and collaborating with a team scattered across time zones. Suddenly, your computer crashes, and hours of work vanish in ...
A STUDY presented at EULAR 2025 has revealed a strong pro-inflammatory gene signature in fibroblasts from patients with very early systemic sclerosis (veSSc), offering new insight into the earliest ...
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