In the 1930s, interest in indole intensified when it became known that the indole substituent is present in many important alkaloids, known as indole alkaloids (e.g., tryptophan and auxins), …

Indole, first isolated in 1866, has the molecular formula C 8 H 7 N, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered.

Jun 24, 2025 · Indole is an aromatic, heterocyclic organic compound with a dual nature regarding its scent. In high concentrations, it has an intense fecal odor, yet in very dilute solutions, it …

Indole has enhanced the incidence of bladder cancer in some bioassays, for example, addition of indole to a diet containing 2-acetylaminofluorene produced an increased incidence of bladder …

The indole nucleus is an important element of many natural and synthetic molecules with significant biological activity. This review covers some of the relevant and recent achievements …

Learn about indole, its chemical properties, synthesis methods, biological role, applications in industry, and key analysis techniques used in research and industry.

Indole is a heterocyclic aromatic organic compound composed of a benzene ring fused to a five-membered nitrogen-containing pyrrole ring. It is a key structural component found in various …

Aug 25, 2025 · Indole is a naturally occurring organic compound found widely in the environment and within living organisms. This molecule is recognized for its unique chemical structure, …

Indole is a nitrogen-containing heterocycle used in the total synthesis of compounds such as goniomitine, [1] (−)-isatisine A, [2] and (±)-aspidospermidine. [3] It is used as an electron donor …

The Fischer indole synthesis is a chemical reaction that produces the aromatic heterocycle indole from a (substituted) phenylhydrazine and an aldehyde or ketone under acidic conditions. [1][2] …