📚Meet MedChemExpress Series | What is #PROTAC ? Unlock it in 40 Seconds 🧬PROTAC, short for PROteolysis-TArgeting Chimeras, is a heterobifunctional nanomolecule with two ligands: one for the target protein and one for the E3 ubiquitin ligase, connected by a linker to form a "ternary complex": Target Protein Ligand – Linker – E3 Ligase Ligand. ✅Once inside the cell, the target protein ligand binds its target while the E3 ligase ligand recruits E3, forming a POI–Linker–E3 complex. E3 ubiquitinate
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