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Researchers at the University of Utah published this in Molecular Psychiatry in September 2025. They found two different types of microglia, which are immune cells inside your brain, that have opposite effects on anxiety. One type suppresses anxiety and the other type promotes it. Basically a built in brake and accelerator fighting each other. The reason this is a big deal is because every anxiety medication on the market targets neurons. Not immune cells. So if this research holds up, it could
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Central sensitization = your nervous system turns the volume up on pain In chronic back pain, the issue isn’t always ongoing injury - it’s that the brain and spinal cord become over-responsive, amplifying normal signals into pain. That’s why some patients hurt even when imaging looks “normal.” Pain is real but it’s being processed differently. Understanding that changes how we treat it. #backpain #centralsensitization #chronicpain
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