Nadi shodhana Pranayama ensures that the whole body is nourished by an extra supply of oxygen. The beneficial effects of practicing Nadi shodhana Pranayama on body functions and ability to combat stressors in our daily life has been well recorded in our ancient yogic books. Yogic discipline aims at disciplining of organ system functions acting at cortical level. Objectives: The present study aimed at comparing the immediate effect of Nadi shodhana Pranayama practice on blood glucose level, heart